哈佛大学-生物医学科研「生物化学与分子药理学」科研

一、课题方向

Immunology

免疫学

Immune disease

免疫疾病

Cancer cell

癌细胞

Immune system

免疫系统

Treatment and immunity

治疗和免疫

Tumour

肿瘤

Cancer

癌症

二、导师背景

生物化学与分子药理学

哈佛医学院与达纳法伯癌症研究所

三、科研内容参考

Discovery, determination and molecular understanding of divergent roles of the p110α and p110β isoforms of PI3K in cellular signaling, metabolism and tumorigenesis.

Identification and therapeutic implication of the unique role PI3K-p110β that is critical in oncogenic signaling and tumorigenesis in the setting of PTEN-deficiency.

Creation of first-in-kind kinome-wide kinase libraries and identification of novel kinase targets in cancer.

Overcoming therapeutic resistance: From mouse models to human therapy.